FactoryBean threw exception on object creation; nested exception is java.lang.IllegalArgumentException: Invalid registry store file /home/tomcat/.dubbo/dubbo-registry-172.18.80.56.cache, cause: Failed to create directory /home/tomcat/.dubbo!
at org.springframework.beans.factory.annotation.AutowiredAnnotationBeanPostProcessor.postProcessPropertyValues(AutowiredAnnotationBeanPostProcessor.java:334)
at org.springframework.beans.factory.support.AbstractAutowireCapableBeanFactory.populateBean(AbstractAutowireCapableBeanFactory.java:1214)
at org.springframework.beans.factory.support.AbstractAutowireCapableBeanFactory.doCreateBean(AbstractAutowireCapableBeanFactory.java:543)
at org.springframework.beans.factory.support.AbstractAutowireCapableBeanFactory.createBean(AbstractAutowireCapableBeanFactory.java:482)
at org.springframework.beans.factory.support.AbstractBeanFactory 1.getObject(AbstractBeanFactory.java:306)
at org.springframework.beans.factory.support.DefaultSingletonBeanRegistry.getSingleton(DefaultSingletonBeanRegistry.java:230)
at org.springframework.beans.factory.support.AbstractBeanFactory.doGetBean(AbstractBeanFactory.java:302)
at org.springframework.beans.factory.support.AbstractBeanFactory.getBean(AbstractBeanFactory.java:197)
at org.springframework.beans.factory.support.DefaultListableBeanFactory.findAutowireCandidates(DefaultListableBeanFactory.java:1192)
at org.springframework.beans.factory.support.DefaultListableBeanFactory.doResolveDependency(DefaultListableBeanFactory.java:1116)
at org.springframework.beans.factory.support.DefaultListableBeanFactory.resolveDependency(DefaultListableBeanFactory.java:1014)
at org.springframework.beans.factory.annotation.AutowiredAnnotationBeanPostProcessor$AutowiredFieldElement.inject(AutowiredAnnotationBeanPostProcessor.java:545)
原因：由于dubbo的注册中心配置，会在当前用户下创建一个文件，默认路径为/home/{user}/.dubbo/dubbo-registry-xxx.cache，主要是用于缓存注册中心地址列表及服务提供者列表,应用重启时将基于此文件恢复，然而我们生产环境的tomcat服务是虚拟用户tomcat启动的，dubbo创建的文件路径则为/home/tomcat/.dubbo/dubbo-registry-xxx.cache，但是这个目录是不存在的，因此就出现了上述日志的报错。
解决方案：
1、使用自定义的路径，dubbo提供了对应的XML属性配置，，file的值为tomcat用户有读写权限的目录，比如tomcat目录下的temp文件夹
${catalina.home}/temp/dubbo-registry-xxx.cache，
2、使用真实用户启动tomcat，并保证该用户有读写权限（现实情况不允许）；
注意：多个dubbo的地址不要配置到同一个文件内，两个注册中心不能使用同一文件存储，xxx为注册中心的服务地址