This problem is entangled for a long time, tried N ways, what changes debug mode, debug what platform, what allows code is not the same, what with the clean-up are all, still can not hit a breakpoint,
Finally found the problem: remove enable the "Just My Code" after the OK,
Enable second point from https://www.cnblogs.com/LuoEast/p/7837881.html change or not change will not affect!